VThunter
a database for single-cell screening of virus target cells in animal kingdom
...
Rat

Scientific Name: Rattus norvegicus

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Euarchontoglires-> Glires-> Rodentia-> Myomorpha-> Muroidea-> Muridae-> Murinae

...
Severe acute respiratory syndrome coronavirus 2

Family: Coronaviridae

Receptor: NRP1

Receptor NRP1 information

Summary: This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. This protein has also been determined to act as a co-receptor for SARS-CoV-2 (which causes COVID-19) to infect host cells. [provided by RefSeq, Nov 2020] [NCBI]  [Proteinatlas]

Data Source

Data set information

Project Date Technology Tissue Condition Cell PMID/DOI
Vthunter_1001 2019.12 10X Genomics Lung Normal 5029 Link
Vthunter_1002 2019.12 10X Genomics Lung Normal 5924 Link
Vthunter_1009 2017.11 Fluidigm C1 UrogenitalSinus Normal 114 Link
Vthunter_110073 2019.12 MARS-seq TotalBrain Normal 2304 Link
Featureplot of receptors

Featureplot of receptors

mRNA expression of NRP1 in human tissues   [NCBI]

Expression: Broad expression in placenta (RPKM 53.3), fat (RPKM 49.6) and 24 other tissues

Protein expression of NRP1 in human tissues   [Proteinatlas]